讲座嘉宾：Xiaoyun Xu教授，帝国理工学院 

讲座时间：4月6日（周三）  14:30-15:30 

讲座地点：木兰船建大楼A211室 

邀请人：梁夫友  特别研究员，上海交通大学-千叶大学国际合作研究中心（SJTU-CU ICRC ）

讲座摘要：

        This talk will address two different research topics: (1) our recent work on multiscale modelling of clot formation and thrombolysis, and (2) a multi-physics model of drug transport in solid tumours. In the first part, examples of patient-specific models  of  type  B  aortic  dissection  and  our  newly  developed  thrombolysis model  will  be presented. The second part of the talk will be focused on an integrated modelling framework that couples drug transport in tumour interstitium and cellular responses through apoptosis signalling. Our most recent work on computational modelling of thermosensitive liposomal delivery of anticancer drugs activated by high intensity focused ultrasound will also be discussed. 

主讲嘉宾简历：

         Prof. Xiao Yun Xu is a Professor of Biofluid Mechanics in the Department of Chemical Engineering at Imperial College London.  She joined Imperial College in 1998 as a Lecturer, and became a full Professor in 2009. She received her BSc and MSc degrees in Thermo-Fluids Engineering from Dalian University of Technology in China, and her PhD in Mechanical Engineering from the City University, London. Her research interests include biomedical engineering and bioprocessing, with a special focus on transport processes in biological and physiological systems. She led a group which did most of the pioneering work on the development of image- based computational models for blood flow in large arteries, and the first image-based carotid artery fluid-wall coupled model developed by her group was reported by various media, including BBC online news and Science (“How the Blood Flows”, Science, Vol. 290, November 2000). Her current research activities include cardiovascular fluid mechanics and mass transport, multiscale and multiphysics modelling of thrombus formation, clot dissolution in thrombolytic therapies, and drug delivery to solid tumour, rheological behaviour of biomass suspensions and multiphysics modelling of bioreactors.   She has co-authored 123 articles in peer-reviewed journals, and supervised 40 PhD students. In 2009, she received the Imperial College Rector‘s Award for Excellence in Research Supervision for her exceptional contributions in providing a supportive learning environment for postgraduate research students.